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December 4, 2025Stroke Vascular and Interventional NeurologyOpen Access

Smoking's Impact on Outcomes After Mechanical Thrombectomy for Acute Ischemic Stroke

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Authors

SNS. Naqvi

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Implication

Retrospective cohort study shows smoking increases 90-day mortality but does not enhance functional recovery in acute ischemic stroke patients, suggesting confounding factors.

Key Points

  • Increased 90-day mortality was associated with smoking status after mechanical thrombectomy for acute ischemic stroke.
  • Smoking led to lower modified Rankin Scale scores at discharge and 3 months in initial unadjusted analysis, indicating better recovery.
  • Multivariable logistic regression adjusted for age, NIHSS, and other factors showed smoking did not relate to better outcomes or recanalization success.
  • Further research is needed to explore mechanisms causing mortality risk in smokers after mechanical thrombectomy.

Cite This Study

S. Naqvi (2025) studied this question.

synapsesocial.com/papers/6930e8dbea1aef094cca3dd2https://doi.org/10.1161/svi270000_285
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Smoking Paradox: Impact of Smoking on Recanalization in the Setting of Intra-Arterial Thrombolysis2014 · 22 citations
  2. 2Smoking-Thrombolysis Paradox2013 · 79 citations
  3. 3Impact of Stroke Severity on the Smoking Paradox in Patients Treated with Intravenous Thrombolysis2022 · 4 citations
  4. 4Influence of Differences in Case Mix on the Better Outcome of Smokers after Intravenous Thrombolysis for Acute Cerebral Ischemia2012 · 17 citations
  5. 5Association of smoking with myocardial injury and clinical outcome in patients undergoing mechanical reperfusion for ST-elevation myocardial infarction2016 · 6 citations