Lipid profile pattern and different abo blood groups of apparently healthy students in college of health technology, calabar, cross river state

This study was done to see whether the possibility of using blood groups as predictive factors for diseases associated with metabolism of lipids. Lipid profile was tested in one hundred (100) apparently healthy students in College of Health Technology, Calabar consisting of forty (40) males and sixty (60) females of different ABO blood groups aged between 18 and 30 years. Lipid profile parameters were analyzed according to enzymatic assay using a commercial kit from Randox laboratories, United Kingdom and Calculation using Friedewaldꞌs equation. Monoclonal ABO blood grouping reagent by Rapid Labs Limited, United Kingdom was used to determine the blood groups. Of these, 22 were blood group A, 17 were blood group B, 4 were blood group AB and 57 were blood group O. Total cholesterol (5.28±0.89mmol/L), triglycerides (2.45±0.66mmol/L) and very low density lipoprotein (1.15±0.30mmol/L) were highest in blood group AB while high density lipoprotein (1.70±0.51mmol/L) were lowest compared to other blood groups. Blood group A had the highest level of low density lipoprotein (1.99±0.33mmol/L) compared to other blood groups. Blood group O showed the highest level of high density lipoprotein (2.95±1.74mmol/L) compared to other blood groups. The study showed that blood group AB might have a higher tendency for diseases associated with lipid metabolism while blood group O may have a lower risk for such diseases. Other risk factors such as family history and environmental factors should also be considered in assessing diseases associated with lipid metabolism.