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December 6, 2025Stroke Vascular and Interventional NeurologyOpen Access

Efficacy and Safety of Dual Antiplatelet Therapy in Acute Ischemic Stroke Patients

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Recurrent ischemic stroke rates were similar between aspirin and dual antiplatelet therapy groups, showing no significant advantage in treatment outcomes.
Among matched patients, recurrent ischemic stroke occurred in 12.2% of the aspirin group compared to 12.6% in the dual therapy group.
Observational analysis from over 2,500 patients using electronic health records assessed efficacy and safety outcomes with various treatment pathways.
These findings indicate that dual antiplatelet therapy after thrombolysis does not improve safety outcomes or recurrent ischemic stroke rates compared to aspirin alone.

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Retrospective cohort study shows dual antiplatelet therapy does not significantly improve outcomes in acute ischemic stroke post-thrombolysis, indicating similar rates of ischemic stroke, safety, and

Cite This Study

Stupin et al. (2025) studied this question.

synapsesocial.com/papers/69337ce8b3f947a0a125a246 https://doi.org/10.1161/svi270000_273

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Implication

Retrospective cohort study shows dual antiplatelet therapy does not significantly improve outcomes in acute ischemic stroke post-thrombolysis, indicating similar rates of ischemic stroke, safety, and

Efficacy and Safety of Dual Antiplatelet Therapy in Acute Ischemic Stroke Patients

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Discussion

Implication

Cite This Study

Efficacy and Safety of Dual Antiplatelet Therapy in Acute Ischemic Stroke Patients

Key Points

Discussion

Implication

Cite This Study

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