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December 8, 2025BloodOpen Access

Perioperative use of efanesoctocog alfa in Hemophilia A: A dual-center real-world study

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Authors

KAKadhim Al-BanaaADAnnette von Drygalski

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Overview

Real-world findings demonstrate effective hemostasis and low postoperative bleeding rates in adults with hemophilia A using efanesoctocog alfa, suggesting safer surgical management.

Key Points

  • To evaluate the effectiveness and safety of efanesoctocog alfa for perioperative management in adults with hemophilia A.
  • Retrospective review of surgeries at two Hemophilia Treatment Centers
  • Included adults with hemophilia A receiving efanesoctocog alfa
  • Collected data on demographics, dosing, bleeding outcomes, and complications.
  • 58 surgeries in 48 patients, with intraoperative hemostasis achieved in all cases
  • Postoperative bleeding occurred in 10% of surgeries but was all minor and manageable
  • No thromboembolic events were observed during the study period.

Cite This Study

Al-Banaa et al. (2025) studied this question.

synapsesocial.com/papers/693624dd4fa91c937236d23dhttps://doi.org/10.1182/blood-2025-3069
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Successful surgical management in severe hemophilia A patients using efanesoctocog alfa: A two-case experience undergoing orthopedic surgery2025
  2. 2Clinical experience with efanesoctocog alfa in patients with uncover needs on emicizumab2025
  3. 3Tailored prophylaxis in severe hemophilia A: Real-world experience with efanesoctocog alfa2025
  4. 4Clinical and Surgical Experiences with Efmoroctocog Alfa in Pediatric Population with Hemophilia A2025
  5. 5Quality of life and functional improvements with efanesoctocog alfa in patients with moderate-to-severe Hemophilia A: A real-world survey2025