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September 23, 2025Clinical and Applied Thrombosis/HemostasisOpen Access

Clinical and Surgical Experiences with Efmoroctocog Alfa in Pediatric Population with Hemophilia A

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Authors

HSHüseyin Avni SolğunGaziantep Children's HospitalMÖMustafa ÖzayGaziantep Children's Hospital

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Implication

Retrospective observational study reports surgical management with efmoroctocog alfa in hemophilia A, suggesting effective prophylaxis.

Key Points

  • Efmoroctocog alfa effectively aided surgical management in patients with hemophilia A, indicating potential for improved outcomes.
  • Among 18 patients, surgical procedures were performed successfully under efmoroctocog alfa treatment, showcasing its safety.
  • This retrospective observational study highlighted the treatment's application in previously untreated and treated patients with severe fviii deficiency.
  • Ehl fviii products like efmoroctocog alfa may decrease treatment burdens while enhancing bleed protection, suggesting promising prophylactic benefits.

Cite This Study

Solğun et al. (2025) studied this question.

synapsesocial.com/papers/68d473a631b076d99fa6bf39https://doi.org/10.1177/10760296251377646
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prophylaxis with a recombinant factor VIII Fc in hemophilia A: long-term follow-up on joint health, efficacy, and safety from phase 3 studies in children and adults2023 · 8 citations
  2. 2Recombinant factor VIII Fc fusion protein for the treatment of severe haemophilia A: Final results from the ASPIRE extension study2020 · 76 citations
  3. 3Extended Half-Life (EHL) Coagulation Factors: A New Era in the Management of Haemophilia Patients2019 · 39 citations
  4. 4Gene therapy in haemophilia: literature review and regional perspectives for Turkey2022 · 11 citations
  5. 5Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A2013 · 445 citations