August 5, 2025Hematology ReportsOpen Access

Advantages of FVIII-Extended Half-Life (Turoctocog Alfa Pegol) in the Management of Cardiac Surgery in a Patient with Mild Hemophilia A: A Case Report and Literature Review

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Authors

ANAngela NapolitanoUniversity of Padua AVAndrea VenturiniAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia MRMonica RonzoniVita-Salute San Raffaele University

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Implication

Case report demonstrates the efficacy of extended half-life factor VIII in preventing bleeding complications in cardiac surgery, suggesting improved perioperative management.

Key Points

The case illustrates the benefits of using extended half-life FVIII in managing hemophilia A during cardiac surgery.
A 73-year-old male with mild hemophilia A underwent aortic valve replacement without postoperative bleeding complications.
An anti-hemorrhagic protocol based on extended half-life recombinant FVIII was successfully implemented perioperatively.
Further studies are necessary to confirm the efficacy and safety of extended half-life FVIII in similar surgical settings.

Cite This Study

Napolitano et al. (2025) studied this question.

synapsesocial.com/papers/689522009f4f1c896c428f04 https://doi.org/10.3390/hematolrep17040041

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Implication

Case report demonstrates the efficacy of extended half-life factor VIII in preventing bleeding complications in cardiac surgery, suggesting improved perioperative management.

Advantages of FVIII-Extended Half-Life (Turoctocog Alfa Pegol) in the Management of Cardiac Surgery in a Patient with Mild Hemophilia A: A Case Report and Literature Review

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Implication

Key Points

Cite This Study

Advantages of FVIII-Extended Half-Life (Turoctocog Alfa Pegol) in the Management of Cardiac Surgery in a Patient with Mild Hemophilia A: A Case Report and Literature Review

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Implication

Key Points

Cite This Study

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