What type of study is this?

This is a Cohort Study study (also classified as: Pre-Registered Trial).

December 8, 2025Blood

Real world experience of patient outcomes in a dedicated clonal hematopoiesis hematology clinic

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Retrospective analysis shows high risk of myeloid neoplasm in patients with clonal hematopoiesis, highlighting the need for dedicated care.

This research focuses on patient outcomes in a dedicated clonal hematopoiesis hematology clinic.
Retrospective study of patients referred to HALT Clinic between March 2022 and March 2025
Collected demographic data and complete blood counts
Analyzed mutational profiles and risk stratified using CHRS and CCRS
143 referrals to the HALT clinic; 80 for suspected clonal hematopoiesis (CH)
76% of CH patients had CHIP/CCUS; 3 progressed to acute myeloid leukemia
High risk identified in 25% of CH patients by prognostic models

Moreira et al. (2025) studied this question.

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Retrospective analysis shows high risk of myeloid neoplasm in patients with clonal hematopoiesis, highlighting the need for dedicated care.