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December 8, 2025BloodOpen Access

Trends in thromboembolism-related mortality among patients with hematologic malignancies in the u.S., 1999–2023: A CDC wonder analysis

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Analysis reveals increasing thromboembolism mortality trends in hematologic malignancies, highlighting significant disparities among populations.

This research aimed to analyze trends in thromboembolism-related mortality among patients with hematologic malignancies in the U.S. from 1999 to 2023.
Extracted mortality data from CDC WONDER database from 1999 to 2023.
Identified cases using ICD-10 codes for hematologic malignancies and thromboembolic events.
Calculated Age-Adjusted Mortality Rate and Crude Mortality Rate per 100,000 individuals.
Performed Joinpoint regression analysis to assess changes in annual percent change.
Identified 19,324 deaths due to thromboembolism-related mortality in hematologic malignancies from 1999 to 2023.
Overall mortality was stable until 2018, increased significantly from 2018 to 2021, then declined.
Female mortality increased significantly from 2014 to 2023, while males saw sharp increases from 2018 to 2021, followed by declines.
Non-Hispanic Black individuals experienced the highest mortality rates and significant increases from 2015 to 2023.

Ahmad Iftikhar (2025) studied this question.

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December 8, 2025BloodOpen Access

View Full Paper

Ask AI

Bookmark

Authors

Analysis reveals increasing thromboembolism mortality trends in hematologic malignancies, highlighting significant disparities among populations.

This research aimed to analyze trends in thromboembolism-related mortality among patients with hematologic malignancies in the U.S. from 1999 to 2023.
Extracted mortality data from CDC WONDER database from 1999 to 2023.
Identified cases using ICD-10 codes for hematologic malignancies and thromboembolic events.
Calculated Age-Adjusted Mortality Rate and Crude Mortality Rate per 100,000 individuals.
Performed Joinpoint regression analysis to assess changes in annual percent change.
Identified 19,324 deaths due to thromboembolism-related mortality in hematologic malignancies from 1999 to 2023.
Overall mortality was stable until 2018, increased significantly from 2018 to 2021, then declined.
Female mortality increased significantly from 2014 to 2023, while males saw sharp increases from 2018 to 2021, followed by declines.
Non-Hispanic Black individuals experienced the highest mortality rates and significant increases from 2015 to 2023.

Ahmad Iftikhar (2025) studied this question.

View Full Paper

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