Temporal trends in mortality from hematological cancers with atrial fibrillation and flutter as contributing causes in the United States, 2000–2020: A national vital statistics system analysis
Cross-sectional analysis shows increasing mortality from hematological cancers with atrial fibrillation, indicating significant comorbidity and sex disparities.
Key Points
This research aims to analyze mortality trends related to hematological cancers and comorbid atrial fibrillation/flutter over two decades.
Cross-sectional analysis using CDC's National Vital Statistics System data from 2000-2020.
Inclusion of deaths caused by hematological malignancies with AF/AFL as a comorbidity.
Joinpoint regression to identify trends and significant inflection points in mortality rates.
31,720 total cases of mortality with a mean age at death of 79.82 years.
Mortality among those with haematological cancers and AF/AFL increased by 300% from 1999 to 2020.
Sex disparities showed a 3.6-fold greater mortality increase in males compared to females.