Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025Blood

Age-related differences in outcomes and treatment patterns of iron deficiency anemia in patient's with crohn's disease

View Full Paper
Ask AI
Bookmark
Share

Authors

KBKarecia ByfieldAUAngimar UrieperoTATinsae Anebo

Discussion

Loading...

Member takes

Overview

Retrospective analysis shows elderly patients with Crohn's Disease and IDA have worse outcomes, indicating urgent need for better management.

Key Points

  • To compare clinical outcomes of elderly and younger patients with Crohn's Disease and iron deficiency anemia.
  • Utilized data from US Collaborative Network-TriNetX
  • Stratified patients into age groups: 18-64 years and 65 years and older
  • Propensity score matched based on demographics, therapeutics, and lab values
  • Outcomes assessed included mortality, blood transfusion needs, parenteral iron therapy, heart failure, and ED visits
  • Elderly patients had a 3.09 times higher mortality rate (p < 0.0001)
  • Increased heart failure risk (HR: 2.27, p < 0.0001)
  • Higher need for blood transfusions (HR: 1.23, p: 0.007)
  • Reduced rate of ED visits (HR: 0.89, p: 0.001)
  • Less frequent parenteral iron therapy (HR: 0.87, p: 0.02)

Cite This Study

Byfield et al. (2025) studied this question.

synapsesocial.com/papers/69362f634fa91c937236ddd8https://doi.org/10.1182/blood-2025-2901
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Predictive value of iron deficiency anaemia on the one-year disease course in inflammatory bowel disease patients in clinical and biochemical remission2026
  2. 2Iron deficiency and anaemia in people with inflammatory bowel disease: do we have an ongoing issue of care quality? Crohn's Colitis Cure data insights programme2025 · 2 citations
  3. 3#1078 Prevalence of iron deficiency in patients admitted to a geriatric unit: analysis according to the stages of chronic kidney disease2024
  4. 4Iron Deficiency Among Hospitalized Patients With Congestive Heart Failure2024 · 1 citations
  5. 5P0790Comparison of Oral and Intravenous Iron Therapy in Patients with Inflammatory Bowel Disease: Efficacy, Safety, Patient-Centered Outcomes, and Cost-Effectiveness2026