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June 1, 2025Journal of the Association of Physicians of India0 citations

Study of Correlation of Iron Profile of Elderly Patients with Heart Failure in a Tertiary Care Center

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NRNeelam RedkarPRPrakash Ram RelwaniSMSaurabh Leeladhar Mandaknalli

Key Result

Iron deficiency was highly prevalent (73.19%) in elderly patients with heart failure and was significantly associated with lower ejection fraction and worse NYHA functional class.

Study Design

Type

Observational (n=138)

Multicenter

No

Structured PICO

P
Population
138 elderly patients with heart failure admitted to a tertiary care hospital in India, evaluated for iron deficiency over a 1-year period.
O
Outcome
Correlation of heart failure severity (ejection fraction and NYHA class) with serum iron, serum ferritin, and percentage transferrin saturation (%TSAT)surrogate

Iron deficiency is highly prevalent in elderly heart failure patients and correlates with worse ejection fraction and higher NYHA functional class.

Abstract

INTRODUCTION: Heart failure (HF) and iron deficiency anemia (IDA) are both common in the elderly, especially in India, and the relative paucity of data about the same makes their relationship worthwhile to study. Also, as IDA, especially nutritional, is relatively simple to manage, it can help in reducing disease burden significantly. OBJECTIVE: To examine the clinical and etiological profile of patients with HF in the elderly age-group and correlate HF with serum iron, serum ferritin, and percentage transferrin saturation (%TSAT). MATERIALS AND METHODS: The present prospective, observational sectional study was carried out in a tertiary care hospital, for a duration of 1 year. The study population included 138 elderly patients admitted to medicine wards and intensive care unit (ICU) having HF. RESULTS: Among the 138 patients with HF included in the study [41.30% in the age-group of 61-65 years, 70.29% males, 35.51% having ejection fraction 50%, which was statistically significant. Absolute or functional ID was revealed maximum in NYHA class IV while it was found least in class I. CONCLUSION: ID was associated with severe and more symptomatic HF in the elderly. The results highlight that iron supplementation through diet and medicines will help to decrease mortality, morbidity, and financial burden of the healthcare system.

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Cite This Study

Redkar et al. (2025) conducted an observational in Heart failure (n=138). Iron deficiency was evaluated on Prevalence of iron deficiency and correlation with ejection fraction and NYHA class. Iron deficiency was highly prevalent (73.19%) in elderly patients with heart failure and was significantly associated with lower ejection fraction and worse NYHA functional class.

synapsesocial.com/papers/6aa0f0f6052b4a3e4c1a0843https://doi.org/10.59556/japi.73.1022
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