Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025Blood

Impact of prolonged hospitalization on outcomes in acute leukemia: A national inpatient sample analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

ASAshish SharmaPCPavan Challa

Discussion

Loading...

Member takes

Overview

Retrospective cohort study links prolonged hospitalization to increased mortality and complications in acute leukemia patients, suggesting healthcare resource implications.

Key Points

  • To assess the impact of prolonged hospitalization on outcomes in patients with acute leukemia.
  • Retrospective cohort study using the National Inpatient Sample from 2019 to 2021.
  • Included adult patients (≥18 years) with a primary diagnosis of acute lymphoblastic leukemia or acute myeloid leukemia using ICD-10-CM codes.
  • Defined prolonged hospitalization as length of stay exceeding 14 days.
  • Utilized multivariable logistic regression to analyze correlations with mortality and complications.
  • 24.3% of patients required prolonged hospitalization.
  • Higher in-hospital mortality for longer stays (10.2% vs. 6.1%).
  • Increased incidence of sepsis in patients with longer stays (31.5% vs. 14.8%).
  • Higher likelihood of ICU admission (18.6% vs. 9.2%).
  • Significantly higher hospitalization costs ($112,400 vs. $68,900).

Cite This Study

Sharma et al. (2025) studied this question.

synapsesocial.com/papers/69362f694fa91c937236dec0https://doi.org/10.1182/blood-2025-6840
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inpatient outcomes in acute myeloid leukemia: A contemporary national study.2026
  2. 2Impact of protein energy malnutrition on hospitalized patients with acute myeloid and lymphoid leukemia: A United States population-based cohort study.2024
  3. 3Effect of Hospital Teaching Status on Mortality and In-Hospital Outcomes in Patients Hospitalized With Acute Leukemia: A National Study2024
  4. 4Impact of interhospital transfer on inpatient outcomes in Acute Myeloid Leukemia2025
  5. 5In-hospital outcome of patients hospitalized for leukemia with comorbid acute decompensated heart failure: An analysis of National Inpatient Sample (NIS).2024 · 1 citations