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December 8, 2025BloodOpen Access

An open-label rollover study to assess the long-term safety of ixazomib

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Authors

DYDok Hyun YoonOBOliver BechterXPXuejun Peng

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Overview

Open-label study assesses ixazomib safety in 32 patients, suggesting favorable findings for long-term therapy outcomes.

Key Points

  • To evaluate the long-term safety profile of ixazomib in patients with multiple myeloma, amyloidosis, and lymphoma.
  • Open-label, multicenter, rollover study
  • Included 32 patients who previously tolerated ixazomib
  • Monitored treatment-emergent adverse events and other safety measures
  • 71.9% received ixazomib monotherapy
  • 68.8% experienced at least one treatment-emergent adverse event
  • No evidence of cumulative or late-onset toxicity observed

Cite This Study

Yoon et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e276https://doi.org/10.1182/blood-2025-7547
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