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December 12, 2025Infectious Diseases and TherapyOpen Access

Long-Term Antibody Persistence After Hepatitis A Vaccination in Healthy Toddlers: Insights from Modeling

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Assess long-term antibody persistence after hepatitis A vaccination in toddlers.
Analyzed antibody levels post-vaccination
Evaluated one- and two-dose schedules of HAV vaccine
Utilized modeling techniques to assess immunity duration
Single dose of HAV vaccine elicits long-lasting immunity
Two-dose schedule shows similar immune responses
Long-term protection confirmed in healthy toddlers

Implication

Modeling reveals long-term protection from HAV vaccine in toddlers after a single dose, suggesting effective immunity.

Abstract

The HAV vaccine, Avaxim®, administered as one- or two-dose schedule, elicited long-lasting immunity in children, with a single dose sufficient to ensure long-term protection.

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Cite This Study

Espul et al. (2025) studied this question.

synapsesocial.com/papers/6940190c2d562116f28f62e9 https://doi.org/10.1007/s40121-025-01278-0

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Implication

Modeling reveals long-term protection from HAV vaccine in toddlers after a single dose, suggesting effective immunity.

Abstract

The HAV vaccine, Avaxim®, administered as one- or two-dose schedule, elicited long-lasting immunity in children, with a single dose sufficient to ensure long-term protection.

Long-Term Antibody Persistence After Hepatitis A Vaccination in Healthy Toddlers: Insights from Modeling

Key Points

Implication

Abstract

Discussion

Cite This Study

Long-Term Antibody Persistence After Hepatitis A Vaccination in Healthy Toddlers: Insights from Modeling

Key Points

Implication

Abstract

Discussion

Cite This Study

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