The correlation of lupus anticoagulant and anticardiolipin antibodies with hematological parameters and clinical findings in sickle cell disease at steady state phase

Ahmed M. E. Elkhalifa; Moataz Mohamed Alhasan Ali; Imad Hamad; Omer M Aburaida; Rabei M. Elbadry; Elfatih Mirghani M Salih; Khaled Mohammed Al‐Sayaghi; Mohammed Albalawi; Burhanudin Saha

doi:10.1186/s12959-025-00813-w

December 8, 2025Thrombosis JournalOpen Access

The correlation of lupus anticoagulant and anticardiolipin antibodies with hematological parameters and clinical findings in sickle cell disease at steady state phase

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Key Points

Correlation of lupus anticoagulant and anticardiolipin antibodies with clinical findings in sickle cell disease is significant, pointing to the importance of autoantibodies.
Observational analysis revealed a linkage between these autoantibodies and hematological parameters in patients.
The study highlights the clinical implications of these findings for better understanding sickle cell disease complications.
Further investigations into the role of aPL in sickle cell disease patients during steady state may improve patient management.

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Implication

Observational analysis revealed connections between lupus anticoagulant, anticardiolipin antibodies, and clinical findings in sickle cell disease, suggesting the need for further assessment of these a

Abstract

This research elucidates the incidence of LA and aCL in SCD patients during steady state, linking these autoantibodies to hematological parameters and clinical complications; thus, prospective assessments of aPL in SCD patients are essential.

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Elkhalifa et al. (2025) studied this question.

synapsesocial.com/papers/69401f062d562116f28f9e59 https://doi.org/10.1186/s12959-025-00813-w

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The correlation of lupus anticoagulant and anticardiolipin antibodies with hematological parameters and clinical findings in sickle cell disease at steady state phase

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

The correlation of lupus anticoagulant and anticardiolipin antibodies with hematological parameters and clinical findings in sickle cell disease at steady state phase

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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