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December 8, 2025Angiology

Sex-Specific Trends and Differences in Clinical Outcomes Among Young Patients With Ischemic Stroke

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Authors

SASong Peng AngGeneral CardiologyJCJia Ee ChiaTexas Tech UniversityJIJosé IglesiasRutgers, The State University of New Jersey

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Overview

Analysis of clinical outcomes in ischemic stroke among young adults shows men have more comorbidities, indicating women's better outcomes despite unique risks.

Key Points

  • Young women had lower adjusted odds ratio for mortality compared to men at 0.84, highlighting sex-specific outcomes.
  • Incidence of ischemic stroke rose steadily, with men consistently showing higher rates than women.
  • Observational analysis of 168,310 hospitalizations in young adults aged 18 to 44 from 2016 to 2021 reveals significant trends.
  • Targeted interventions addressing modifiable risk factors are critical to reduce the stroke burden in young men.

Cite This Study

Ang et al. (2025) studied this question.

synapsesocial.com/papers/694020d72d562116f28fa8abhttps://doi.org/10.1177/00033197251392666
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sex differences in etiologies, risk factors, and outcomes among young adult patients with acute ischemic stroke2025 · 2 citations
  2. 2Sex Differences in Ischemic Stroke Within the Younger Age Group: A Register-Based Study2022 · 8 citations
  3. 3Abstract WP113: Stroke in the Young: Sex Differences in Risk Factors, Etiologies, Acute Treatments, and Outcomes in a Nationwide Analysis2026
  4. 4Stroke Hospitalizations Over Three Decades: Lower for Men, Unchanged for Women. A Population-Based Study2014 · 7 citations
  5. 5Impact of sex in stroke in the young2023 · 8 citations