The study shows eriocitrin improves oxidative stress and barrier function in retinal pigment epithelium, suggesting flavonoids may aid dry AMD treatment.
This study demonstrated that eriocitrin alleviates NaIO₃-induced oxidative stress and RPE barrier dysfunction by modulating the SIRT7/YAP/ATP7A signaling pathway and inhibiting cuproptosis. Our findings indicated eriocitrin as a promising natural therapeutic candidate for dry AMD and lay the foundation for developing flavonoid-based anti-cuproptosis strategies.
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Wang et al. (2025) studied this question.
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