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December 7, 2025Precision NanomedicineOpen Access

Targeted Delivery of Raloxifene via RGD-functionalized Chitosan Nanoparticle Selectively Attenuates Breast Tumor Growth

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Authors

AYAmit Singh YadavGKGopal C. Kundu

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Overview

Nanotechnology demonstrates therapeutic effectiveness against breast cancer by promoting apoptosis and reducing tumor growth.

Key Points

  • Tumor growth significantly decreases with Raloxifene-loaded nanoparticles in breast cancer models, suggesting improved treatment effectiveness.
  • In vivo imaging confirmed the targeted delivery of nanoparticles, leading to reduced angiogenesis within tumors.
  • Utilizing RGD-functionalized chitosan nanoparticles, this approach enhances cellular absorption and stability in the tumor environment.
  • This method supports targeted therapies for breast cancer, which may mitigate the toxic side effects of conventional treatments.

Cite This Study

Yadav et al. (2025) studied this question.

synapsesocial.com/papers/694020e82d562116f28fae64https://doi.org/10.33218/001c.147875
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Codelivery of Raloxifene and Rutin as PEGylated Nanoliposomes: Formulation, Characterization, and Prophylactic Activity Against Breast Cancer2025
  2. 2Design and Development of Optimised Nanostructured Polymeric Systems of Raloxifene For Improved Biopharmaceutical Application in Breast Cancer: A Review2025
  3. 3Preparation and Characterization of Raloxifene- and Rutin-Co-loaded Chitosan Nanoparticles for the Treatment of Colon Cancer2026
  4. 4Raloxifene-Loaded Lipid Nanovesicles: A Journey to Select the Optimal Nanocarrier Formulation Through Characterization and Cytotoxic Analysis2025
  5. 5Nanotechnology-Driven Therapeutic Potential of Raloxifene in Osteoporosis and Cancer: A Recent Review2025