This analysis reports the cytotoxic potential of raloxifene-loaded lipid nanovesicles in MCF-7 breast cancer cells, highlighting hexosomes as the most effective formulation.
Key Points
Raloxifene-loaded hexosomes demonstrated superior cytotoxic activity, exhibiting an IC50 of 45.3 µM against MCF-7 cells.
Hexosomes, nanoliposomes, and nanoniosomes were characterized to determine their size, charge, and entrapment efficiency.
The study validated the effectiveness of various nanocarrier formulations through cytotoxic analysis on breast cancer cell lines.
Future research should focus on in vitro characterization studies for the RLX-loaded hexosomal formulation.