December 7, 2025AnimalsOpen Access

An Integrated Model of Biphasic Apoptosis in Avian Coccidiosis: Molecular Networks and Host–Parasite Interplay

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Authors

JHJin Huang KCK.-J. Cheng JWJinrong Wang

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Overview

This review reveals biphasic apoptosis in avian coccidiosis, indicating therapeutic targets and molecular networks involved in host–parasite interaction.

Key Points

Apoptotic regulation in avian coccidiosis exhibits a biphasic pattern, with early inhibition favoring parasites and late activation aiding release.
Key mechanisms include signaling hubs such as PI3K/Akt, NF-κB, and JNK/p38 MAPK coordinating apoptosis.
Insights into the molecular networks and Eimeria dynamics could guide the development of therapeutic targets for control.
Understanding host–parasite interactions is crucial for developing strategies to inhibit coccidiosis effectively.

Cite This Study

Huang et al. (2025) studied this question.

synapsesocial.com/papers/694020f72d562116f28fb1bb https://doi.org/10.3390/ani15243528

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December 7, 2025AnimalsOpen Access

An Integrated Model of Biphasic Apoptosis in Avian Coccidiosis: Molecular Networks and Host–Parasite Interplay

View Full Paper

Ask AI

Bookmark

Authors

JHJin Huang KCK.-J. Cheng JWJinrong Wang

Discussion

Member takes

Overview

This review reveals biphasic apoptosis in avian coccidiosis, indicating therapeutic targets and molecular networks involved in host–parasite interaction.

Key Points

Apoptotic regulation in avian coccidiosis exhibits a biphasic pattern, with early inhibition favoring parasites and late activation aiding release.
Key mechanisms include signaling hubs such as PI3K/Akt, NF-κB, and JNK/p38 MAPK coordinating apoptosis.
Insights into the molecular networks and Eimeria dynamics could guide the development of therapeutic targets for control.
Understanding host–parasite interactions is crucial for developing strategies to inhibit coccidiosis effectively.

Cite This Study

Huang et al. (2025) studied this question.

synapsesocial.com/papers/694020f72d562116f28fb1bb https://doi.org/10.3390/ani15243528

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