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December 1, 2025Dentistry JournalOpen Access

A Rare Case of Mandibular Chondrosarcoma Arising from Fibrous Dysplasia

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Authors

CRCiprian Ioan RoiRCRaluca Maria CloşcaMRMircea Riviș

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Overview

Case report reveals malignant transformation in fibrous dysplasia, highlighting the need for early detection and surgical treatment.

Key Points

  • Malignant transformation leads to chondrosarcoma following surgical intervention in mandibular fibrous dysplasia.
  • Biopsy reveals fibrous dysplasia with a malignant transformation to a tumor, emphasizing rarity of such cases.
  • Observational analysis highlights the challenge of identifying malignant transformation in benign conditions.
  • Early recognition and effective surgical treatment support patient outcomes in rare cases like this one.

Cite This Study

Roi et al. (2025) studied this question.

synapsesocial.com/papers/69402a652d562116f29019edhttps://doi.org/10.3390/dj13120560
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnosis and treatment of myxoid chondrosarcoma in the mandible – case report2025
  2. 2Undifferentiated sarcoma arising from fibrous dysplasia in a young adult2024 · 1 citations
  3. 3Management of Chondrosarcoma of the Mandible2025
  4. 4Mandibular chondrosarcoma grade 2: a case report highlighting disease aggressiveness2026
  5. 5OSTEOSARCOMA OF THE MANDIBLE: A CASE REPORT OF CHONDROBLASTIC VARIANT WITH PATHOLOGICAL AND MOLECULAR INSIGHTS2025