Uniformity Between Serological Biomarker Test, Esophago-gastro-duodenoscopy and Biopsy Histology in Triage of Upper Abdominal Symptoms in Gastroscopy Referral Patients

GP, EGD, and USS do not always provide uniform diagnoses; however, after a negative GP test, the probability of detecting moderate/severe AG using EGD is extremely low (3/447; 0.007%). In the first-line diagnosis of upper abdominal symptoms, substantial cost savings (90%) could be achieved by preserving EGD only for those (<10%) patients whose GP test indicates AG.