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November 26, 2025Journal of Alzheimer s Disease

Disruption of Ca V 2.3 channels in the brain of the 5xFAD mice

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Authors

CACarolina AguadoRARocío Alfaro‐RuizAMAlejandro Martín‐Belmonte

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Aguado et al. (2025) studied this question.

synapsesocial.com/papers/694033db2d562116f2907cfdhttps://doi.org/10.1177/13872877251396963
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nanoarchitecture of Ca<sub>V</sub>2.1 channels and GABA<sub>B</sub> receptors in the mouse hippocampus: Impact of APP/PS1 pathology2024 · 8 citations
  2. 2Disrupted calcium dynamics and electrophysiological activity in the stratum pyramidale and hippocampal alveus during fear conditioning in the 5xFAD model of Alzheimer’s disease2025
  3. 3Early onset of Hyperexcitability of Medial Mammillary Body Neurons in 5XFAD<sup>+</sup> mice—an Early Target of Alzheimer‘s Disease2025 · 1 citations
  4. 4Abstract DP081: Impaired Electro-Calcium Coupling and Reduced Cerebral Blood Flow in the Early Stage of Alzheimer’s Disease2026
  5. 5Cav3 T-Type Voltage-Gated Ca2+ Channels and the Amyloidogenic Environment: Pathophysiology and Implications on Pharmacotherapy and Pharmacovigilance2022 · 2 citations