Key result
Misdiagnosed thymoma in a 16-year-old presents with DVT and intracardiac thrombus.
Why the study?
Thymic tumors are very rare in children, and no prior pediatric reports exist regarding deep vein thrombosis (DVT) and intra-cardiac clots.
Highlights a rare presentation of DVT and intra-cardiac thrombus in a pediatric patient with thymoma, emphasizing the need for accurate immunohistochemical diagnosis and routine DVT assessment.
Answers are grounded in this paper and cite their sources.
May warrant thymoma consideration in select pediatric DVT cases; leaves open standardized IHC protocols and incidence.
A bstract Thymic tumors are very rare in children, and when present, mainly occur in adolescents. Less than 300 pediatric cases have been reported worldwide in literature. There are no reports regarding deep vein thrombosis (DVT) and intra-cardiac clots among the pediatric cases. We report a case of DVT of the right axillary and subclavian veins, with a clot in the right atrium in a 16-year-old male child with thymoma, which was misdiagnosed as non-Hodgkin’s lymphoma on histology but found to be a thymoma on immunohistochemistry. This case report aims to improve awareness regarding DVT and thymomas in children and encourage routine assessment and treatment of DVT for these children for improved outcomes.
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Okosi et al. (2025) studied this question. A 16-year-old male with misdiagnosed thymoma presented with deep vein thrombosis and an intra-cardiac thrombus, highlighting the rarity and diagnostic challenges of thymic tumors in children.
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