Key result
Oral administration of misoprostol was effectively compared with vaginal administration for abortion following mifepristone treatment in the first trimester.
Why the study?
Does oral administration of misoprostol compare to vaginal administration for first-trimester abortion in women treated initially with mifepristone?
Does oral administration of misoprostol compare to vaginal administration for first-trimester abortion in women treated initially with mifepristone?
This study compares oral versus vaginal administration of misoprostol for first-trimester abortion in women initially treated with mifepristone.
Both routes effective after mifepristone, expanding patient choice; confirms equivalence in first-trimester medical abortion.
Medical termination of pregnancy can be successfully performed with a combination of mifepristone (RU 486) and a prostaglandin analogue. We conducted a prospective, randomized trial to compare oral with vaginal administration of the prostaglandin E1 analogue misoprostol for first-trimester abortion in women treated initially with mifepristone.
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El‐Refaey et al. (1995) studied this question. Oral administration of misoprostol was effectively compared with vaginal administration for abortion following mifepristone treatment in the first trimester.
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