Beta-blocker therapy did not reduce all-cause mortality, myocardial infarction, or heart failure in patients with LVEF ≥50% post-myocardial infarction.
Does beta-blocker therapy reduce the incidence of death from any cause, myocardial infarction, or heart failure in patients with an LVEF of at least 50% after myocardial infarction?
In patients with normal ejection fraction (LVEF ≥50%) after myocardial infarction, routine beta-blocker therapy does not reduce the composite of all-cause death, MI, or heart failure.
Absolute Event Rate: 0% vs 0%
In this meta-analysis including individual-patient data from five randomized trials, beta-blocker therapy did not reduce the incidence of death from any cause, myocardial infarction, or heart failure in patients with an LVEF of at least 50% after myocardial infarction without other indications for beta-blockers. (Funded by Centro Nacional de Investigaciones Cardiovasculares Carlos III and others; PROSPERO database number, CRD420251119176.).
Kristensen et al. (Sun,) reported a other. Beta-blocker therapy did not reduce all-cause mortality, myocardial infarction, or heart failure in patients with LVEF ≥50% post-myocardial infarction.