Key result
Patients with diabetes without prior MI have a 43% lower risk of total CHD events compared to non-diabetic patients with previous MI (OR 0.56).
Why the study?
Does diabetes without prior MI confer the same risk of total CHD events as prior MI without diabetes?
Population
Patients with diabetes but no previous myocardial infarction, and patients without diabetes but with…
Comparison
Diabetes without prior myocardial infarction vs No diabetes with previous myocardial infarction
Design
Meta-analysis
Follow-up
mean 13.4 years (range 5-25 years)
Authors
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Diabetes without prior MI may warrant primary rather than secondary prevention intensity; challenges risk-equivalence consensus from observational data.
Does diabetes without prior MI confer the same risk of total CHD events as prior MI without diabetes?
Diabetes without prior myocardial infarction is not a coronary risk equivalent to prior myocardial infarction, suggesting primary prevention strategies should be based on absolute risk rather than a blanket secondary prevention approach.
Bulugahapitiya et al. (2008) studied this question. Patients with diabetes without prior MI have a 43% lower risk of total CHD events compared to non-diabetic patients with previous MI (OR 0.56).
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