Key result
Multi-Link Vision® cobalt chromium stent required a mean balloon deployment pressure of 13.90 atm compared to 11.50 atm for the Multi-Link Zeta® stainless steel stent.
Why the study?
Does a cobalt chromium stent require different balloon deployment pressure for optimal unfolding compared to a stainless steel stent in patients with de novo native coronary stenoses?
RCT (n=18)
null
null
No
Does a cobalt chromium stent require different balloon deployment pressure for optimal unfolding compared to a stainless steel stent in patients with de novo native coronary stenoses?
Effect estimate: null (95% CI null)
Absolute Event Rate: 13.9% vs 11.5%
p-value: p=null
Cobalt chromium stents require higher deployment pressures for optimal unfolding compared to stainless steel stents, and their achieved lumen diameter is more easily overestimated by Quantitative Coronary Analysis.
Target higher balloon pressures for cobalt chromium stent deployment; extends prior stainless steel data to in vivo cobalt chromium performance.
Background Cobalt chromium coronary stents are increasingly being used in percutaneous coronary interventions. There are, however, no reliable data about the characteristics of unfolding and visibility of this stent alloy in vivo . The aim of this study is to compare cobalt chromium coronary stents with conventional stainless steel stents using intracoronary ultrasound. Methods Twenty de novo native coronary stenoses ≤ 20 mm in length (target vessel reference diameter ≥ 2.5 and ≤ 4.0 mm) received under sequential intracoronary ultrasound either a cobalt chromium stent (Multi-Link Vision ® ; n = 10) or a stainless steel stent (Multi-Link Zeta ® ; n = 10). Results For optimal unfolding, the cobalt chromium stent requires a higher balloon deployment pressure (13.90 ± 2.03 atm) than the stainless steel stent (11.50 ± 2.12 atm). Furthermore, the achieved target vessel diameter of the cobalt chromium stent (Visibility-Index QCA/IVUS Multi-Link Vision ® 1.13 / Multi-Link Zeta ® 1.04) is more easily overrated by Quantitative Coronary Analysis. Conclusion These data indicate that stent material-specific recommendations for optimal implantation pressure and different stent material with an equal design should both be considered in interpreting QCA-analysis.
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Hagemeister et al. (2005) conducted an RCT in de novo native coronary stenoses (n=18). Multi-Link Vision® cobalt chromium stent vs. Multi-Link Zeta® stainless steel stent was evaluated on Balloon deployment pressure when IVUS criteria were reached (null, 95% CI null, p=null). Multi-Link Vision® cobalt chromium stent required a mean balloon deployment pressure of 13.90 atm compared to 11.50 atm for the Multi-Link Zeta® stainless steel stent.
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