Chemoselective synthesis of multi-functionalized alkynes and alkenes via transition-metal-free iodination of terminal alkynes

Key Points

• To explore a method for synthesizing multi-functionalized alkynes and alkenes through iodination.
• Conducted chemoselective reactions without transition metals.
• Utilized terminal alkynes containing a heteroatom for iodination.
• Applied various iodination techniques including diiodination and triiodination.
• Successfully synthesized multi-functionalized alkynes and alkenes.
• Achieved high selectivity in the iodination process.
• Showed that the presence of a heteroatom influences the reaction outcome.