What question did this study set out to answer?

The research aims to evaluate the risk of serious infections in inflammatory bowel disease (IBD) patients using corticosteroids versus those not using them.

January 23, 2026Journal of Crohn s and Colitis

DOP123Risk of serious infections in patients with inflammatory bowel disease with or without corticosteroid treatment: A nationwide propensity score-matched cohort study

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Authors

AFAnette ForssKarolinska University Hospital JAJordan E. AxelradNYU Langone Health JSJ SöderlingKarolinska Institutet

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Implication

Nationwide cohort study assesses infection rates in IBD patients with corticosteroids, indicating higher risks compared to non-users.

Key Points

The research aims to evaluate the risk of serious infections in inflammatory bowel disease (IBD) patients using corticosteroids versus those not using them.
Utilized nationwide Swedish registers from 2007 to 2024
Conducted propensity score matching to compare infection rates
Assessed rates of serious and opportunistic infections during different treatment periods
Patients on corticosteroids experienced significantly higher rates of serious infections compared to those not on corticosteroids
Infection rates increased 2-4 times during corticosteroid exposure
Cumulative corticosteroid doses correlated with higher hazard ratios for infections

Cite This Study

Forss et al. (2026) studied this question.

synapsesocial.com/papers/69730fe2c8125b09b0d1fa4e https://doi.org/10.1093/ecco-jcc/jjaf231.160

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DOP123Risk of serious infections in patients with inflammatory bowel disease with or without corticosteroid treatment: A nationwide propensity score-matched cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

DOP123Risk of serious infections in patients with inflammatory bowel disease with or without corticosteroid treatment: A nationwide propensity score-matched cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

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