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January 24, 2026International Journal of Stroke

Sex Differences in Mortality and Functional Outcomes Across Stroke Subtype: A Nationwide Cohort Study

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Authors

TKTae Jung KimJLJi Sung LeeJKJun Yup Kim

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Overview

National cohort study examines sex differences in mortality and outcomes across stroke subtypes, indicating the need for tailored care approaches.

Key Points

  • The study aims to investigate sex differences in long-term mortality and functional outcomes in stroke patients, categorized by stroke subtype.
  • Retrospective cohort design using linked clinical audit and claims data from South Korea.
  • Analyzed 58,429 acute stroke patients across 269 hospitals from 2018 to 2021.
  • Outcomes assessed included all-cause mortality and functional status at discharge.
  • Utilized multivariable Cox and logistic regression to evaluate sex associations with outcomes.
  • Females showed lower mortality rates across all stroke subtypes after adjustments.
  • Functional outcomes varied by subtype; worse for females in ischemic strokes but better in hemorrhagic strokes.
  • Males received more reperfusion and surgical treatments, while females accessed more rehabilitation services.

Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/69746126bb9d90c67120b127https://doi.org/10.1177/17474930261419672
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sex disparities in comorbidities, one-year functional outcome and mortality after ischemic stroke: a population-based study.2026
  2. 2Predictors of functional outcome after stroke: Sex differences in older individuals2024 · 18 citations
  3. 3Sex Differences in Long-Term Mortality and Functional Outcome After Rehabilitation in Patients With Severe Stroke2020 · 43 citations
  4. 4Sex Differences in Management and Outcome After Stroke2003 · 330 citations
  5. 5Acute Care, Secondary Prevention, and Outcomes after Ischaemic and Haemorrhagic Stroke in Men and Women: A Data-Linkage Study2024 · 1 citations