Abnormal papillary muscle morphology is independently associated with increased left ventricular outflow tract obstruction in hypertrophic cardiomyopathy

Key Result

Abnormal papillary muscle morphology is associated with increased resting left ventricular outflow tract gradient in patients with hypertrophic cardiomyopathy, independent of septal thickness.

Key Points

• This research examines the relationship between abnormal papillary muscle morphology and left ventricular outflow tract obstruction in hypertrophic cardiomyopathy patients.
• Patients with hypertrophic cardiomyopathy were assessed for papillary muscle morphology and resting left ventricular outflow tract gradient.
• Septal thickness was measured and analyzed to determine its relationship with the LVOT gradient.
• Patients with abnormal papillary muscles exhibited a higher resting left ventricular outflow tract gradient than those with normal morphology.
• The association between abnormal papillary muscle morphology and increased LVOT gradient remained significant after adjusting for septal thickness.