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February 2, 2026The Heart Surgery Forum0 citationsOpen Access

The Establishment of a Transaxillary Minimally Invasive Aortic Valve Replacement Program: Considerations and First Patient Outcomes

JGJohannes GöklerPSPhilipp SzalkiewiczFHF Huber

Key Result

Transaxillary minimally invasive aortic valve replacement is feasible with low complication rates and favorable clinical outcomes during the initiation phase of the program.

Key Points

  • To evaluate the outcomes of aortic valve surgery using the novel right transaxillary approach.
  • Conducted a trial between June 2023 and May 2025 with 22 patients
  • Utilized the right transaxillary approach for aortic valve surgeries
  • Monitored outcomes including surgical times, complications, and ICU stay
  • Median aortic clamp time was 78.5 minutes
  • One patient experienced a stroke and another required a pacemaker
  • The median ICU stay was 1.0 days with no deaths reported during follow-up

Study Design

Type

Observational (n=22)

Multicenter

No

Structured PICO

P
Population
22 patients undergoing aortic valve surgery, median age 64.5 (60.0–70.0) years, 63.6% female, at a single center in Austria. Key indications: severe aortic valve stenosis (77.3%) or severe aortic valve regurgitation (22.7%).
I
Intervention
Minimally invasive aortic valve surgery using the right transaxillary (rTX) access, primarily with peripheral cardiopulmonary bypass cannulation via the right groin.
O
Outcome
Procedural feasibility and clinical outcomes including mortality, stroke, pacemaker implantation, bleeding, and intensive care unit stay at median 6.0 months follow-up.safety

The right transaxillary approach for minimally invasive aortic valve surgery is feasible and safe, demonstrating 0% mortality and low complication rates in an early program experience.

Limitations

  • Retrospective single-center study
  • Small sample size
  • Short follow-up
  • retrospective single-center study
  • small sample size
  • short follow-up
  • precise quantification of postoperative pericardial effusion was not possible

Abstract

Background: As minimally invasive and alternative approaches for aortic valve repair gain increased popularity, this trial reports on outcomes of an established program using the underreported novel right transaxillary (rTX) access for aortic valve surgery. Methods: Between June 2023 and May 2025, a total of 22 patients underwent aortic valve surgery using the rTx approach (female: n = 14 (63.6%); age: 64.5 (60.0–70.0) years; EuroSCORE II: 0.9 (0.6–1.1)), mainly for aortic valve stenosis (n = 17 (77.3%)) and primarily with cannulation of the right groin (n = 21 (95.5%)) for cardiopulmonary bypass (CPB). Results: The median aortic clamp time was 78.5 (74.8–90.3) minutes, and the median extracorporeal circulation time was 143.0 (134.8–178.3) minutes. One (4.5%) patient underwent acute surgical revision via sternotomy due to bleeding from the aortotomy, while aortic root replacement was successfully performed. One (4.5%) patient experienced a stroke, and one (4.5%) received a pacemaker for high-grade atrioventricular block. Regarding CPB and surgical access site complications, one (4.5%) patient had a postoperative hematoma at the right groin, and one (4.5%) had a surgically revised thoracic hematoma. The median intensive care unit stay was 1.0 (1.0–2.3) days. No patient died during the median follow-up period of 6.0 (3.0–16.5) months. Conclusion: Minimally invasive aortic valve surgery by rTX is feasible for a variety of valve pathologies, revealing good clinical outcomes even at the start of such a program. The low learning curve at experienced centers for minimally invasive cardiac surgery encourages other centers to adopt this approach as the potential future standard for aortic valve surgery.

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Cite This Study

Gökler et al. (2026) conducted an observational in aortic valve disease (n=22). transaxillary minimally invasive aortic valve replacement was evaluated on Postoperative complications including stroke, pacemaker implantation, and new onset of atrial fibrillation. Transaxillary minimally invasive aortic valve replacement is feasible with low complication rates and favorable clinical outcomes during the initiation phase of the program.

synapsesocial.com/papers/6980fbf6c1c9540dea80dce5https://doi.org/10.31083/hsf49908
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