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February 2, 2026Stroke

Abstract DP088: The Role of Sex and Age in Acute Ischemic Stroke

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Authors

MHMargaret HoughtonLGLisa E. GuthrieSLSarah Langston

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Overview

Secondary data analysis reveals significant sex differences in outcomes after acute ischemic stroke in adults, suggesting targeted interventions may be needed.

Key Points

  • This study aims to assess the impact of sex and age on symptoms, care, and outcomes in acute ischemic stroke patients.
  • Conducted a secondary data analysis of records from the Get With the Guidelines-Stroke Registry.
  • Included patients diagnosed with acute ischemic stroke from January 1, 2022, to December 31, 2024.
  • Grouped patients by their arrival method to the Comprehensive Stroke Center for comparison.
  • Analyzed NIHSS and mRS scores to find differences between male and female patients.
  • 1,801 patient records were reviewed, with some excluded based on inclusion criteria.
  • Significant differences were found in age, initial NIHSS scores, and discharge mRS scores between male and female patients.
  • Statistical analysis indicated differences with a p-value less than 0.05 for the observed metrics.

Cite This Study

Houghton et al. (2026) studied this question.

synapsesocial.com/papers/6980fd3cc1c9540dea80ef6dhttps://doi.org/10.1161/str.57.suppl_1.dp088
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sex differences in stroke outcomes: a retrospective analysis2025
  2. 2Gender Differences in Acute Ischemic Stroke2009 · 153 citations
  3. 3Sex Disparity in the Access of Elderly Patients to Acute Stroke Care2007 · 115 citations
  4. 4Abstract WP113: Stroke in the Young: Sex Differences in Risk Factors, Etiologies, Acute Treatments, and Outcomes in a Nationwide Analysis2026
  5. 5Sex differences in ischaemic stroke care and outcomes. A longitudinal Scottish national data-linkage study2025