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This research examines how maternal slow-release nitrogen diets during late gestation affect offspring skeletal muscle energy metabolism.

February 2, 2026PLoS ONEOpen Access

Maternal slow-release nitrogen diets during late gestation optimize the energy metabolism in calves’ skeletal muscle

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Experimental diets optimize energy metabolism in calves’ skeletal muscle, suggesting benefits from maternal nutrition.

This research examines how maternal slow-release nitrogen diets during late gestation affect offspring skeletal muscle energy metabolism.
Compared two dietary groups: Control with low protein and Slow-released nitrogen during late gestation.
Performed muscle biopsies on calves for RNA sequencing and proteomic analysis at 45 days old.
Identified enriched biological processes and protein expression differences in skeletal muscle.
Proteomic analysis showed significant differences in protein expression between dietary treatments.
Key biological processes included ATP metabolism, glucose metabolism, and energy metabolism pathways.
Maternal nitrogen supplementation positively influences postnatal energy metabolism in calves.

Costa et al. (2026) studied this question.

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