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February 2, 2026Journal of Veterinary Diagnostic InvestigationOpen Access

Salpingitis and multiorgan lesions caused by highly pathogenic avian influenza A(H5N1) virus in a cat associated with consumption of recalled raw milk in California

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Authors

HAHernando D. AcevedoEBEmily BeelerBCBeate Crossley

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Overview

Case report reveals severe lesions in a cat after consuming recalled raw milk, indicating health risks.

Key Points

  • To present a case of a cat with severe illness linked to HPAI A(H5N1) virus from raw milk consumption.
  • Postmortem examination and diagnostic workup conducted on the cat.
  • Histopathology and immunohistochemistry used to identify lesions and viral presence.
  • Molecular detection performed for HPAI A(H5N1) virus.
  • Cat exhibited lesions such as salpingitis, necrotizing pneumonia, and hydrothorax.
  • Consistent intralesional immunolabeling for influenza A virus detected in multiple organs.
  • Molecular confirmation of HPAI A(H5N1) virus, clade 2.3.4.4b, genotype B3.13 in tissues.

Cite This Study

Acevedo et al. (2026) studied this question.

synapsesocial.com/papers/6980ff37c1c9540dea81213chttps://doi.org/10.1177/10406387251413563
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 20242024 · 544 citations
  2. 2Serologic Evidence of Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Veterinary Professional Exposed to an Infected Domestic Cat — Los Angeles County, California, December 2024–January 20252026 · 5 citations
  3. 3Clinical Course, Laboratory Findings, and Tissue Distribution of Highly Pathogenic Avian Influenza A(H5N1) Virus in a Naturally Infected Domestic Cat2026
  4. 4Highly pathogenic avian influenza A H5N1 virus infection in an immunocompromised domestic cat2025
  5. 5H5N1 Clade 2.3.4.4b Infections in Domestic Cats During an Avian Influenza Outbreak in Italy: Implications for One Health Surveillance2026