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February 2, 2026Open Access

A Case Report: Drug-Induced Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis Overlap

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The report describes a case of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis overlap induced by itraconazole and cefadroxil.
Describes clinical symptoms and timeline of drug administration.
Identifies skin lesions and their characteristics after treatment initiation.
Details management approach including drug discontinuation and supportive care.
Patient developed fluid-filled and erythematous lesions following drug treatment.
Diagnosis of SJS-TEN overlap confirmed due to severe skin involvement.
Patient responded well to corticosteroids and cyclosporine, leading to stable recovery.

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Case report reveals drug-induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis overlap in an adult, highlighting urgent intervention needs.

Alpa P. Gor2 Rachana D. Rathavi*1 (2026) studied this question.

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Case report reveals drug-induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis overlap in an adult, highlighting urgent intervention needs.