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June 10, 2026Open Access

Severe Stevens-Johnson Syndrome Induced by Antibiotic Therapy: A Case Report

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Authors

GDGokulakrishnan D.MSMirudula S.KMKavya M.

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Overview

Case report reveals severe Stevens-Johnson syndrome triggered by antibiotic therapy in an adult, highlighting the need for prompt intervention.

Key Points

  • The central aim is to present a case of Stevens-Johnson syndrome induced by antibiotic therapy and emphasize the importance of timely recognition and treatment.
  • Described a case of a 34-year-old female with severe reactions following cotrimoxazole use.
  • Conducted dermatological examination and laboratory investigations to establish diagnosis.
  • Provided treatment including corticosteroids, intravenous fluids, and nutritional support.
  • Patient presented with high-grade fever, rash, and mucosal lesions indicating severe Stevens-Johnson syndrome.
  • Epidermal detachment involved approximately 12% body surface area, confirmed by positive Nikolsky sign.
  • Complete clinical recovery was achieved after 14 days of hospitalization following appropriate management.

Cite This Study

D. et al. (2026) studied this question.

synapsesocial.com/papers/6a28ffc76f82f25be989c889https://doi.org/10.5281/zenodo.20593148
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Stevens-Johnson Syndrome: Case Report and Literature Review2026
  2. 2CEFTRIAXONE-INDUCED STEVENS–JOHNSON SYNDROME: A RARE CASE REPORT2026
  3. 3A Rare Case of Stevens-Johnson Syndrome in a Young Patient Presenting With Odynophagia Following Antibiotic Use2026
  4. 4A case of delayed-onset Stevens–Johnson syndrome following co-amoxiclav administration in a 98-year-old female2026 · 1 citations
  5. 5A Rare Case of Stevens-Johnson Syndrome Secondary to Levofloxacin Administration: Presentation and Management2026 · 1 citations