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This case report aims to describe a rare instance of Stevens-Johnson syndrome following levofloxacin administration and its management.

April 8, 2026CureusOpen Access

A Rare Case of Stevens-Johnson Syndrome Secondary to Levofloxacin Administration: Presentation and Management

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A rare case describes severe SJS following levofloxacin use in an elderly woman, highlighting management challenges and the need for vigilance.

This case report aims to describe a rare instance of Stevens-Johnson syndrome following levofloxacin administration and its management.
Presented a case of a 74-year-old woman with SJS after taking levofloxacin.
Detailed the clinical features including severe mucocutaneous ulceration and ocular involvement.
Discussed the multidisciplinary care approach applied for the patient's condition.
Patient developed extensive mucocutaneous ulceration within days of antibiotic exposure.
Ocular involvement was profound, requiring specialized care.
Management involved an intensive coordinated effort across multiple medical disciplines.

Chrysostomou et al. (2026) studied this question.

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A rare case describes severe SJS following levofloxacin use in an elderly woman, highlighting management challenges and the need for vigilance.