What question did this study set out to answer?

To report an atypical case of Stevens-Johnson syndrome associated with Mycoplasma pneumoniae in an adolescent with isolated mucosal involvement.

March 22, 2026American Journal of Case ReportsOpen Access

A Rare Case of Stevens-Johnson Syndrome in a Young Patient Presenting With Odynophagia Following Antibiotic Use

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Authors

JTJohn Tomasini JSJoanna Sajdlowska GCGregory Crisafulli

Discussion

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Overview

A case report demonstrates atypical mycoplasma pneumoniae-associated Stevens-Johnson syndrome in a young male, suggesting early diagnosis is critical for outcomes.

Key Points

To report an atypical case of Stevens-Johnson syndrome associated with Mycoplasma pneumoniae in an adolescent with isolated mucosal involvement.
Case report of an 18-year-old male with odynophagia and oral ulcerations after antibiotic use.
Laboratory evaluation for inflammatory markers and serologic testing for Mycoplasma pneumoniae.
Initial management included antibiotic cessation, intravenous fluids, and corticosteroids.
Patient developed macular lesions and progressive mucosal sloughing during hospitalization.
Serologic tests confirmed elevated Mycoplasma pneumoniae IgM and IgG titers.
The patient showed gradual improvement and full recovery after 2 weeks of treatment with intravenous immunoglobulin and azithromycin.

Cite This Study

Tomasini et al. (2026) studied this question.

synapsesocial.com/papers/69bf86ecf665edcd009e9001 https://doi.org/10.12659/ajcr.951823

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March 22, 2026American Journal of Case ReportsOpen Access

A Rare Case of Stevens-Johnson Syndrome in a Young Patient Presenting With Odynophagia Following Antibiotic Use

View Full Paper

Ask AI

Bookmark

Authors

JTJohn Tomasini JSJoanna Sajdlowska GCGregory Crisafulli

Discussion

Member takes

Overview

A case report demonstrates atypical mycoplasma pneumoniae-associated Stevens-Johnson syndrome in a young male, suggesting early diagnosis is critical for outcomes.

Key Points

To report an atypical case of Stevens-Johnson syndrome associated with Mycoplasma pneumoniae in an adolescent with isolated mucosal involvement.
Case report of an 18-year-old male with odynophagia and oral ulcerations after antibiotic use.
Laboratory evaluation for inflammatory markers and serologic testing for Mycoplasma pneumoniae.
Initial management included antibiotic cessation, intravenous fluids, and corticosteroids.
Patient developed macular lesions and progressive mucosal sloughing during hospitalization.
Serologic tests confirmed elevated Mycoplasma pneumoniae IgM and IgG titers.
The patient showed gradual improvement and full recovery after 2 weeks of treatment with intravenous immunoglobulin and azithromycin.

Cite This Study

Tomasini et al. (2026) studied this question.

synapsesocial.com/papers/69bf86ecf665edcd009e9001 https://doi.org/10.12659/ajcr.951823

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