Key result
Adrenalectomy resolves severe pheochromocytoma-induced Takotsubo syndrome in a patient with cardiogenic shock.
Why the study?
Pheochromocytoma can cause transient cardiomyopathy resembling Takotsubo syndrome, but diagnosis is often challenging due to the tumour's rarity and non-specific, paroxysmal symptoms.
Case Report (n=1)
Early recognition and mechanical circulatory support as a bridge to surgery can lead to full recovery in patients with severe cardiogenic shock due to pheochromocytoma-induced Takotsubo syndrome.
May support screening for pheochromocytoma in unexplained Takotsubo shock; extends case evidence but leaves generalizability open.
Pheochromocytoma is a rare catecholamine-secreting tumour that can cause transient cardiomyopathy resembling Takotsubo syndrome due to catecholamine excess. Its diagnosis is often challenging because of the tumour’s rarity and the non-specific, often paroxysmal nature of symptoms. We present the case of a previously healthy woman in her 30s who developed non-specific symptoms, including nausea, vomiting and palpitations, progressing to cardiogenic shock with severely impaired biventricular function requiring mechanical circulatory support. Further investigations revealed a pheochromocytoma-induced Takotsubo syndrome, which was successfully treated with adrenalectomy. This case report supports current evidence that early recognition and aggressive supportive care, including mechanical circulatory support as a bridge to surgery, can lead to full recovery from severe catecholamine-induced cardiac dysfunction.
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Corraro et al. (2026) conducted a case report in Pheochromocytoma-induced Takotsubo syndrome (n=1). Mechanical circulatory support and adrenalectomy was evaluated. Mechanical circulatory support as a bridge to adrenalectomy successfully treated severe cardiogenic shock secondary to pheochromocytoma-induced Takotsubo syndrome in a young woman.
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