Key result
Percutaneous LAA closure shows low embolic risk despite ~62% device permeability, though bleeding remains frequent.
Why the study?
A high device permeability rate has been reported following percutaneous LAA closure, but its clinical significance and relationship with cardiovascular events remain uncertain.
What is the relationship between cardiac CT findings (permeability) and cardiovascular events during follow-up after percutaneous left atrial appendage closure?
Population
140 patients who underwent percutaneous LAA closure
Design
Single-center retrospective study
Follow-up
24.3 ± 14.7 months
Authors
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Low embolic events despite permeability after LAA closure may support less intensive antithrombotics; leaves open prospective validation of CT findings.
Cohort (n=140)
No
What is the relationship between cardiac CT findings (permeability) and cardiovascular events during follow-up after percutaneous left atrial appendage closure?
Despite a high rate of device permeability on follow-up CT, embolic events after LAA closure remain low, whereas bleeding events are frequent, supporting the consideration of less aggressive antithrombotic regimens.
Guijarro et al. (2025) conducted a cohort in Contraindications for anticoagulation or embolic recurrences (n=140). Percutaneous left atrial appendage closure was evaluated on Thrombotic events. Percutaneous left atrial appendage closure resulted in a 6.4% rate of thrombotic events and 22.9% rate of hemorrhagic events, despite a 62.2% device permeability rate on CT.