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February 6, 2026European Heart Journal

Association of abdominal obesity with metabolic multimorbidity and death across glycemic spectrum

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Authors

JLJ J LiLLL LeiZZZ Zhao

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Overview

Cohort analysis shows that abdominal obesity increases metabolic abnormalities and mortality in individuals across the glycemic spectrum, highlighting health risks.

Key Points

  • This research aims to explore the relationship between abdominal obesity and metabolic conditions, as well as all-cause and cardiovascular mortality across different diabetes statuses.
  • Cohort analyses of participants aged 20 to 74 from the National Health and Nutrition Examination Survey (NHANES) from 1988 to 1994.
  • Examination of associations between abdominal obesity and metabolic indicators, mortality data, and diabetes status.
  • Assessment of prevalence rates and odds for various metabolic abnormalities related to abdominal obesity.
  • Among 11,580 participants, prevalence of non-diabetic abdominal obesity was 19.7%, that with prediabetes was 12.6%, and that with diabetes was 4.9%.
  • Abdominal obesity in individuals with diabetes was associated with a significantly higher number of metabolic abnormalities (OR: 30.36).
  • Individuals with abdominal obesity and dysglycemia had increased risks of all-cause death and cardiovascular death, with HRs of 1.22 and 1.51 for prediabetes, and 1.69 and 1.99 for diabetes, respectively.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/698586118f7c464f23009e6ahttps://doi.org/10.1093/eurheartj/ehaf784.3804
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Also Consider

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