Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 6, 2026Health Science ReportsOpen Access

Abdominal Obesity Phenotypes and Incidence of Type 2 DM, Cardiovascular Outcomes and All‐Cause Mortality—A Systematic Review and Meta‐Analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

SDSoraya DoustmohamadianSemnan University of Medical SciencesMMMarjan MomeniSemnan University of Medical SciencesMMMajid MirmohammadkhaniSemnan University of Medical Sciences

Discussion

Loading...

Member takes

Implication

Systematic review reveals abdominal obesity affects type 2 diabetes and cardiovascular disease risk in adults, implying significant health concerns.

Key Points

  • This review aims to assess the relationship between abdominal obesity phenotypes and health outcomes such as type 2 diabetes, cardiovascular disease, and mortality.
  • Conducted a systematic search across multiple databases to find relevant prospective cohort studies in adults.
  • Included studies compared metabolically healthy abdominal obese individuals to metabolically healthy non-abdominally obese controls.
  • Pooled estimates were calculated using random-effects meta-analysis and heterogeneity was assessed.
  • Six studies with 98,329 participants were included.
  • Metabolically unhealthy individuals showed high risks of type 2 diabetes and cardiovascular disease compared to controls.
  • MHAO individuals had risks of type 2 diabetes and mortality similar to MHNAO controls, indicating potential benign characteristics.

Cite This Study

Doustmohamadian et al. (2026) studied this question.

synapsesocial.com/papers/69faa2b504f884e66b533562https://doi.org/10.1002/hsr2.72028
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Are Metabolically Healthy Overweight and Obesity Benign Conditions?2013 · 976 citations
  2. 2Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 20212025 · 1,097 citations
  3. 3Analysis of Changes in Weight, Waist Circumference, or Both, and All-Cause Mortality in Chinese Adults2022 · 91 citations
  4. 4Exercise‐Induced Reduction in Obesity and Insulin Resistance in Women: a Randomized Controlled Trial2004 · 700 citations
  5. 52. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—20182017 · 3,230 citations