Key result
Diabetes is linked to ~24% AT recurrence after LVA ablation, exceeding non-diabetic rates.
Why the study?
Low-voltage area ablation after PVI may improve persistent AF outcomes but increase atrial tachycardia recurrence, and its effect across diabetic status was unclear.
Does additional LVA ablation affect atrial tachycardia recurrence patterns in diabetic versus non-diabetic patients with persistent atrial fibrillation?
RCT (n=343)
1:1
Does additional LVA ablation affect atrial tachycardia recurrence patterns in diabetic versus non-diabetic patients with persistent atrial fibrillation?
Absolute Event Rate: 61% vs 50%
Additional low-voltage area ablation after pulmonary vein isolation in persistent AF increases the incidence of atrial tachycardia recurrence predominantly in diabetic patients.
No takes yet. Share an insight, caveat, or question.
Caution LVA ablation in diabetics due to higher AT recurrence; challenges broad adjunctive use in persistent AF.
Inoue et al. (2025) conducted an RCT in persistent atrial fibrillation (n=343). Additional low-voltage area (LVA) ablation vs. Pulmonary vein isolation (PVI) alone was evaluated on 1-year freedom from AF/AT recurrence without antiarrhythmic drugs. Additional low-voltage area ablation after pulmonary vein isolation resulted in 61% versus 50% 1-year freedom from arrhythmia recurrence, but significantly increased atrial tachycardia in diabetics.
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