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February 8, 2026Antimicrobial Resistance and Infection Control0 citationsOpen Access

Antimicrobial locks for the prevention of central line associated bloodstream infections in pediatric patients: a systematic review and network meta-analysis

NLNathan L’EtoileYLYun LIEHEricka Hayes

Key Points

  • This review aims to assess the effectiveness of antimicrobial locks in preventing central line associated bloodstream infections (CLABSI) in pediatric patients.
  • Conducted a systematic review and network meta-analysis of existing studies on antimicrobial locks.
  • Focused on primary and secondary prevention of CLABSI in pediatric populations.
  • Evaluated differences in efficacy based on the type of antimicrobial lock used.
  • Found a need for well-designed studies to confirm the effectiveness of antimicrobial locks.
  • Indicated potential differences in impact based on lock type, requiring further investigation.

Abstract

This review highlights the need for well-designed studies to determine the clinical effectiveness of antimicrobial locks for primary and secondary CLABSI prevention in specific pediatric populations and to determine whether there is differential impact by lock type.

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Cite This Study

L’Etoile et al. (2026) studied this question.

synapsesocial.com/papers/698827f00fc35cd7a8847001https://doi.org/10.1186/s13756-026-01704-z
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