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February 8, 2026Japanese Journal of Clinical Oncology

Clinical utility of the Geriatric-8 in the functional assessment of patients with gynecological cancer aged 75 and older: a retrospective study

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Authors

MYMiwa YasakaYKYumi KawaguchiCMChinami Makinoda

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Overview

Retrospective analysis explores G8 scores affecting treatment decisions in older women with gynecological cancer, suggesting implications for care quality.

Key Points

  • To evaluate the role of the Geriatric-8 score in assessing the functional status and treatment outcomes for older women with gynecological cancer.
  • Retrospective analysis of data from 180 women aged ≥75 with gynecological malignancies.
  • Assessment of pre-treatment G8 scores to categorize patients as fit or frail.
  • Examination of associations between G8 scores and patient demographics, disease characteristics, and treatment responses.
  • 29.4% of patients were classified as fit and 70.6% as frail based on G8 scores.
  • Frail patients had a higher need for long-term care and more frequent anticoagulant use.
  • Median G8 scores differed by cancer type, with endometrial cancer scoring highest and vulvar cancer lowest.
  • Surgical and chemoradiotherapy patients had higher G8 scores than those receiving best supportive care or chemotherapy.

Cite This Study

Yasaka et al. (2026) studied this question.

synapsesocial.com/papers/698828620fc35cd7a8847e16https://doi.org/10.1093/jjco/hyag020
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