Key result
A structured diagnostic protocol yields final diagnoses in 62% of MINOCA patients regardless of sex.
Why the study?
MINOCA represents a diagnostic and therapeutic challenge, and little data are available regarding sex differences in its diagnostic work-up and diagnostic yield.
Does the diagnostic work-up and diagnostic yield of protocolized diagnostics for MINOCA differ between male and female patients?
Does the diagnostic work-up and diagnostic yield of protocolized diagnostics for MINOCA differ between male and female patients?
Despite sex differences in the utilization of specific diagnostic modalities for MINOCA, a structured diagnostic protocol yields a final diagnosis in approximately 62% of patients regardless of sex.
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Protocolized MINOCA evaluation yields similar diagnoses across sexes despite modality differences; leaves open whether sex-tailored testing improves outcomes.
Yosofi et al. (2025) studied this question. A structured diagnostic protocol established final diagnoses in 62% of MINOCA patients with no sex difference, despite differences in testing modalities used.
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