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The central aim is to develop TPU membranes with controlled antibiotic release for effective wound healing.

Electrospun TPU Nanofibrous Membranes Incorporating Ciprofloxacin–Montmorillonite Nanoclays for Sustained Drug Release and Wound Healing

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The central aim is to develop TPU membranes with controlled antibiotic release for effective wound healing.
Developed TPU membranes via electrospinning
Incorporated ciprofloxacin-loaded montmorillonite nanoclays
Performed structural and chemical analyses using X-ray diffraction and FTIR
Conducted drug release, cytotoxicity, and antibacterial assays
CIP-loaded MMT membranes exhibited slower drug release rates (12.4%–20.8% over 6 days) compared to direct CIP embedding (59.1%–73.4%)
Good biocompatibility observed in pure TPU membranes with >85% viability
MMT-containing membranes showed reduced cell viability over time
Only CIP-containing membranes inhibited growth of Staphylococcus aureus and Escherichia coli

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Demonstrates sustained drug release in wound healing applications using TPU membranes incorporating ciprofloxacin and montmorillonite.

Çalışkan et al. (2026) studied this question.

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