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February 14, 2026Journal of PregnancyOpen Access

Evaluation of Serum Lactate Dehydrogenase and Electrolyte Levels Among Preeclamptic Women at the University of Gondar Comprehensive Specialized Hospital, Northwest, Ethiopia: A Comparative Cross‐Sectional Study

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Authors

ETEndeshaw Yitayew TamirieAmbo UniversityHEHiwot Tezera EndaleUniversity of GondarMZMuluken Fekadie Zerihun

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Implication

Comparative cross-sectional study demonstrates elevated LDH and decreased electrolytes in preeclamptic women, suggesting effective management strategies.

Key Points

  • This research aims to evaluate serum lactate dehydrogenase and electrolyte levels among preeclamptic women compared to healthy pregnant women.
  • Conducted a comparative cross-sectional study with 128 participants.
  • Classified preeclamptic women into those with and without severe features.
  • Measured serum LDH and electrolyte levels using a Beckman Coulter 700 AU analyzer.
  • Analyzed data with one-way ANOVA and receiver operator characteristic curve.
  • Significant elevation of LDH in preeclamptic women compared to healthy controls (p < 0.001).
  • Notable decreases in magnesium, calcium, and potassium levels in preeclamptic women versus healthy women.
  • Elevated LDH in severe preeclampsia, with significant reductions in calcium and potassium compared to non-severe cases.
  • LDH demonstrated excellent diagnostic accuracy for preeclampsia at ≥ 350 U/L.

Cite This Study

Tamirie et al. (2026) studied this question.

synapsesocial.com/papers/699010f22ccff479cfe573a2https://doi.org/10.1155/jp/9970060
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